Evidence-Based Skin Health. No Shortcuts. No Myths.

At Pellelixir, we believe in transparency, science, and protecting your skin — and your health.

While injectable glutathione is often marketed as a "skin whitening" shortcut, the truth is starkly different: there is no solid scientific evidence that intravenous (IV) glutathione lightens skin safely or effectively.

The Science: Does IV Glutathione Lighten Skin?

Multiple published studies have investigated this claim — and the results are disappointing:

A 2020 review of available studies concluded that systemic glutathione is not sufficiently effective as a skin-whitening agent, with only limited and temporary changes observed in specific body areas.
A pilot study published in the Journal of Plastic Dermatology found that IV glutathione injections showed no statistically significant lightening of skin tone after 10 weeks of treatment.
A randomized controlled trial in Pakistan reported that only 37.5% of participants showed slight tone improvement, and those effects diminished after stopping treatment.

What Regulators Say

Both U.S. and international health authorities have formally discouraged the use of IV glutathione for aesthetic purposes.

The U.S. FDA has not approved any injectable glutathione product for skin lightening. It warns of serious risks including infections, liver and kidney toxicity, and allergic reactions.
The Philippine FDA issued multiple warnings about the unapproved and unsafe use of injectable glutathione, citing potentially life-threatening effects and lack of validated benefit.

What Makes Pellelixir Different

Pellelixir is a serum applied topically to your skin using your fingers. Unlike glutathione injections, Pellelixir works at the cellular level using Glyteine® - the only ingredient proven to rapidly raise intracellular glutathione levels in human cells. This is where real antioxidant protection happens, not in your bloodstream.

Our clinically tested serum:

Boosts cellular glutathione – unlike any other topical or oral serum
Delivers visible brightening and tone evenness in a maximum of 28 days
Is safe, gentle, and dermatologist-approved

No Bleaching. No Whitening Claims. Just Science-Backed Radiance.

We do not—and will never—use injectable glutathione or promote harmful whitening practices.

Pellelixir is about enhancing your skin’s natural glow, protecting it from oxidative stress, and celebrating all skin tones with integrity and evidence.

References

  1. Maran, R.R.M., et al. Systematic review of systemic glutathione in skin whitening. PMC7196133
  2. Diana, J., et al. Intravenous glutathione as a skin lightening agent. Journal of Plastic Dermatology. JPDS 2011
  3. Tanveer, R. et al. Efficacy of IV Glutathione in skin lightening: A double-blind study. JPAD. JPAD Article
  4. U.S. FDA. Concerns over injectable glutathione. FDA Advisory
  5. Philippine FDA. Advisory No. 2019-182: Unsafe use of glutathione as skin lightening agent. FDA Philippines